An Overview of the Neurobiological Effects of Physical Exercise

Introduction The neurobiological effects of physical exercise are numerous and involve a wide range of interrelated effects on brain structure, brain function, and cognition. A large body of research in humans has demonstrated that consistent aerobic exercise (e.g. 30 minutes every day) induces persistent improvements in certain cognitive functions, healthy alterations in gene expression in… Read More


What are the Effects of an Intensive Lifestyle Intervention on Cardiovascular Disease?

Research Paper Title History of Cardiovascular Disease, Intensive Lifestyle Intervention, and Cardiovascular Outcomes in the Look AHEAD Trial. Background To examine the effects of an intensive lifestyle intervention (ILI) on cardiovascular disease (CVD), the Action for Health in Diabetes (Look AHEAD) trial randomised 5,145 participants with type 2 diabetes and overweight/obesity to a ILI or… Read More

What are the Exercise Beliefs & Behaviours of Individuals with Joint Hypermobility Syndrome/Ehlers-Danlos Syndrome – Hypermobility Type?

Research Paper Title Exercise beliefs and behaviours of individuals with Joint Hypermobility syndrome/Ehlers-Danlos syndrome – hypermobility type. Background To explore exercise beliefs and behaviours of individuals with Joint Hypermobility syndrome/Ehlers-Danlos syndrome – hypermobility type and to explore patient experiences of physiotherapy. Methods A cross sectional questionnaire survey design was used to collect quantitative and qualitative… Read More

Mental Health & Exercise: Getting the ‘Dose’ Right

It is now well-known, and generally accepted, that exercise is beneficial for mental health. For example, we know that: 1. Enjoyment Matters Research demonstrates the pleasure response (officially known as affective valence) to a single bout of aerobic exercise can predict participation in the long-term, i.e. six- and twelve months later. The less pleasurable the… Read More

Smoking & the Risk of Injury in Military Personnel

Research Paper Title The Combined Effect of Cigarette Smoking and Fitness on Injury Risk in Men and Women. Background Prior studies have identified cigarette smoking and low fitness as independent risk factors for injury; however, no studies have evaluated the combined effect of cigarette smoking and fitness on injury risk. The objective of this research… Read More

The Motivation to Benefit from Exercise

There is no doubt about the benefits of exercise. Physical activity is associated with a reduced risk of coronary heart disease, obesity, type 2 diabetes, and other chronic diseases and conditions. Despite the wealth of information about the benefits of exercise, sedentary adults often find it hard to  change their behaviour in a sustainable manner. The… Read More

Could Measurement of Circulating CF n-DNA be a Sensitive Tool for Monitoring Acute Exercise Effects in the Human Body?

Research Paper Title Repeated bouts of exhaustive exercise increase circulating cell free nuclear and mitochondrial DNA without development of tolerance in healthy men. Objective Acute single strenuous exercise increases circulating cell free DNA (cf DNA). The researchers tested whether three repeated bouts of exhaustive exercise induced the cf DNA response without development of tolerance in… Read More