Does Diet & Exercise Affect Brain Ageing?

According to de Lucia and colleagues (2020), yes they do. People with certain variants of genes that play a key role in brain ageing seem to respond better to a healthy lifestyle. Some versions of the SIRT1 gene are affected by amount of exercise and some variants of the GRB10 gene by whether people eat… Read More


Can Genetic Perturbations of Inflammatory Response Contribute to the Risk of PTSD?

Research Paper Title Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations. Background Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder that occurs with relatively high frequency after deployment to warzones (∼10%). While twin studies have estimated the heritability to be up to 40%, thus indicating a considerable genetic component in the… Read More

What are the Exercise Beliefs & Behaviours of Individuals with Joint Hypermobility Syndrome/Ehlers-Danlos Syndrome – Hypermobility Type?

Research Paper Title Exercise beliefs and behaviours of individuals with Joint Hypermobility syndrome/Ehlers-Danlos syndrome – hypermobility type. Background To explore exercise beliefs and behaviours of individuals with Joint Hypermobility syndrome/Ehlers-Danlos syndrome – hypermobility type and to explore patient experiences of physiotherapy. Methods A cross sectional questionnaire survey design was used to collect quantitative and qualitative… Read More

What is the Role of Genetic Background in Susceptibility to Chemical Warfare Nerve Agents across Rodent and Non-human Primate Models?

Research Paper Title The role of genetic background in susceptibility to chemical warfare nerve agents across rodent and non-human primate models. Abstract Genetics likely play a role in various responses to nerve agent exposure, as genetic background plays an important role in behavioral, neurological, and physiological responses to environmental stimuli. Mouse strains or selected lines… Read More

Trauma Exposure in US Soldiers: Linking Genetics, Bipolar Disorder & Alcohol Misuse

Research Paper Title Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers. Background To investigate whether trauma exposure moderates the genetic correlation between substance use disorders and psychiatric disorders, we tested whether trauma exposure modifies the association of genetic risks for mental disorders with alcohol misuse and nicotine… Read More

The Patellofemoral Joint: From Dysplasia to Dislocation

Research Paper Title The patellofemoral joint: from dysplasia to dislocation. Abstract Patellofemoral dysplasia is a major predisposing factor for instability of the patellofemoral joint. However, there is no consensus as to whether patellofemoral dysplasia is genetic in origin, caused by imbalanced forces producing maltracking and remodelling of the trochlea during infancy and growth, or due… Read More

Increasing Physical Capacity: Soldiers & Gene Modification

Article Title The Real Captain America: Bioengineering the Super Soldiers of Tomorrow. Extract “With the rapidly advancing field of genomics and gene modification, the distinct possibility has arisen for applying these technologies to enhance a soldier’s physical capacity. Genetic modification or “’gene doping’, already banned from its possible future use in the Olympics, has many… Read More