Mid-Life: Any there any Associations between Fast Food, Physical Activity Environments & Adiposity?

Research Paper Title Associations between fast food and physical activity environments and adiposity in mid-life: cross-sectional, observational evidence from UK Biobank. Background The built environment might be associated with development of obesity and related disorders. We examined whether neighbourhood exposure to fast-food outlets and physical activity facilities were associated with adiposity in UK adults. Methods… Read More

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A Possible Link between Sedentary Lifestyle & Colorectal Tumorigenesis

Research Paper Title Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation. Abstract Pioneering epidemiological work has established strong association of sedentary lifestyle and obesity with the risk of colorectal cancer, while the detailed underlying mechanism remains unknown. Here the researchers show that Hotair (HOX transcript antisense RNA) is a… Read More

The Third Factor: Eating Frequency

Is it the kind of food you eat that makes you fat or how much you eat? The third factor, often ignored, is how often. This research provides some insight into the third factor of eating. Research Paper Title Eating Frequency Is Positively Associated with Overweight and Central Obesity in US Adults. Background Evidence of… Read More

Linking Physical Activity, Mortality & Adiposity

Research Paper Title Physical Activity and All-cause Mortality Across Levels of Overall and Abdominal Adiposity in European Men and Women: The European Prospective Investigation into Cancer and Nutrition Study (EPIC). Background The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number of deaths reduced by eliminating physical inactivity compared… Read More

Linking Fried Food Consumption, Genetic Risk & Body Mass Index

Research Paper Title Fried Food Consumption, Genetic Risk, and Body Mass Index: Gene-diet Interaction Analysis in Three US Cohort Studies. Study Question Does genetic predisposition interact with the effect of fried food consumption on adiposity? Summary Answer The association between fried food consumption and adiposity is strengthened by genetic predisposition; and the genetic influences on… Read More

What is the Link between Adiposity & Cardiometabolic Disease?

A genetic predisposition to obesity is randomly allocated, and mendelian randomisation studies exploit this natural experiment to find out if well established associations between obesity and disease are likely to be causal. The latest study used a genetic variation that increases body mass index (BMI) by 0.36 unit per allele. In analyses pooling 36 observational… Read More