Is Low-dose Aspirin Effective in Increasing Pregnancy & Live Birth among Women with Metabolic Syndrome?

Research Paper Title Metabolic Syndrome and the Effectiveness of Low-dose Aspirin on Reproductive Outcomes. Background Metabolic syndrome is associated with increases in both inflammation and aspirin resistance, but effectiveness of aspirin in improving reproductive health among women with metabolic syndrome is unknown. We evaluated the effectiveness of low-dose aspirin in improving reproductive outcomes across metabolic… Read More

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How Hemp and CBD Oils Could Benefit those in the Military

Both hemp oil and cannabidiol (CBD) oil are gaining popularity among athletes and other individuals who live active lifestyles, putting their body through physical stress (recreational or work-related) on a daily basis. Similarly, the potential benefits to those working or serving in the military seem obvious. However, there are several questions that arise when contemplating… Read More

LSD and the US Army

Research Paper Title LSD experiments by the United States Army. Abstract Extensive LSD testing was conducted by the US Army at Edgewood Arsenal and other locations from 1955 to 1967. A number of different reports have been produced describing the health effects of this testing, including the Veterans Health Initiative Report in 2003. By and… Read More

Investigating N-acetylcysteine as a Possible Pharmacologic Treatment for PTSD & SUD

Research Paper Title A Double-Blind, Randomised, Controlled Pilot Trial of N-Acetylcysteine in Veterans With Post-traumatic Stress Disorder and Substance Use Disorders. Background The antioxidant N-acetylcysteine is being increasingly investigated as a therapeutic agent in the treatment of substance use disorders (SUDs). This study explored the efficacy of N-acetylcysteine in the treatment of post-traumatic stress disorder… Read More

Got Back Pain, Get Paracetamol: Really?

Research Paper Title Efficacy and Safety of Paracetamol for Spinal Pain and Osteoarthritis: Systematic Review and Meta-analysis of Randomised Placebo Controlled Trials. Objective To investigate the efficacy and safety of paracetamol (acetaminophen) in the management of spinal pain and osteoarthritis of the hip or knee. Design Systematic review and meta-analysis. Results 12 reports (13 randomised… Read More

What’s Wrong with Non-regulated Interventions & Trials?

The following article (written by Rafeal Dal-Re, Michael Bracken & John Ioannidis in the BMJ) is a timely reminder to authors, journalists and consumers about the pros and cons of non-regulated interventions and trials. Efforts to promote the availability of data from clinical trials have been led predominantly by regulators (EMA, 2014) or drug companies… Read More

Primary Care & Weight Reduction Interventions: A Happy Marriage?

Research Paper Title Access to Weight Reduction Interventions for Overweight and Obese Patients in UK Primary Care: Population-based Cohort Study. Objectives To investigate access to weight management interventions for overweight and obese patients in primary care. Setting UK primary care electronic health records. Participants A cohort of 91,413 overweight and obese patients aged 30-100 years was sampled from the Clinical… Read More