Penicillin & World War II

During the second world war, chemists made penicillin by culturing moulds in pans. Labs would have these pans stacked to the ceiling, but the process still yielded only tiny amounts of penicillin. The compound was in such short supply that unmetabolised remnants of the drug were being recycled from soldiers’ urine. Reference Howgego, J. (2018) Roaming Free. New Scientist. 19… Read More


Got Back Pain, Get Paracetamol: Really?

Research Paper Title Efficacy and Safety of Paracetamol for Spinal Pain and Osteoarthritis: Systematic Review and Meta-analysis of Randomised Placebo Controlled Trials. Objective To investigate the efficacy and safety of paracetamol (acetaminophen) in the management of spinal pain and osteoarthritis of the hip or knee. Design Systematic review and meta-analysis. Results 12 reports (13 randomised… Read More

Salt & Drugs: Don’t Just be Wary of Food Content!

Research Paper Title Association between Cardiovascular Events and Sodium-containing Effervescent, Dispersible, and Soluble Drugs: Nested Case-control Study. Study Question Do patients taking sodium-containing formulations of prescription drugs have a higher incidence of cardiovascular events than patients taking those same drugs in formulation that do not contain sodium? Summary Answer Patients prescribed sodium-containing effervescent, dispersible, and… Read More