Diagnosing & Managing Vitamin B12 Deficiency

Research Paper Title Vitamin B12 Deficiency. Abstract Vitamin B12 is an essential cofactor that is integral to methylation processes important in reactions related to DNA and cell metabolism, thus a deficiency may lead to disruption of DNA and cell metabolism and thus have serious clinical consequences. Intracellular conversion of vitamin B12 to two active coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in… Read More

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Causes & Measures to Prevent Sudden Cardiac Death in Athletes

Research Paper Title Sudden Cardiac Death in Athletes. Abstract Sudden cardiac death is defined as an unexpected death, occurring usually within one hour from onset of symptoms in cases where the death is witnessed and in unwitnessed cases within 24 hours of the individual last being seen alive and well. Sudden cardiac death in athletes is the leading… Read More

Learning from Soft Power: A Need for Soft Healing in the 21st Century.

Research Paper Title Learning from Soft Power: A Need for Soft Healing in the 21st Century. Abstract The limitations of direct military intervention—“hard power”—for achieving foreign policy are increasingly highlighted by international events. Policy makers, military leaders, and intelligence experts now recognise the crucial role of preventive policy approaches—“soft power”—to tackle the multifaceted, upstream causes of conflict and instability. Soft power… Read More

Bone Density: Calcium Supplements vs Calcium from Dietary Sources

Study Question Does increasing calcium intake from dietary sources have any effects on bone mineral density and, if it does, are they similar to the effects of calcium supplements? Summary Answer Increasing calcium intake, whether from dietary sources or by taking calcium supplements, leads to small (1-2%) non-progressive increases in bone density, without any ongoing… Read More

Olympic Legacy: Sporting Activity has fallen by 400,000 since 2011

The proportion of people in England aged 16 or above taking part in sport at least once a week fell from 36.2% (15,890,400) during the Olympic Games in 2011-12 to 35.5% (15,491,200) in 2014-15. The Local Government Association called for the government and Sport England to redirect some of the £500 million for sport between… Read More

Assessment of Chest Pain in a Low Risk Patient: Is The Exercise Tolerance Test Obsolete?

Discussion Paper Title Assessment of chest pain in a low risk patient: is the exercise tolerance test obsolete? Background This is one of a series of occasional articles that highlight areas of practice where management lacks convincing supporting evidence. The series adviser is David Tovey, editor in chief, the Cochrane Library. To suggest a topic for this series, please… Read More

Is There Any Link Between Soft Drink Intake & Osteoarthritis?

Research Paper Title Soft Drink Intake and Progression of Radiographic Knee Osteoarthritis: Data from the Osteoarthritis Initiative. Background The researchers examined the prospective association of soft drink consumption with radiographic progression of knee osteoarthritis (OA). This was a prospective cohort study which used data from the osteoarthritis initiative (OAI). Methods In OAI, 2149 participants with… Read More