Mice: Linking Aerobic Exercise & Heart Failure

Research Paper Title Aerobic exercise protects against pressure overload-induced cardiac dysfunction and hypertrophy via β3-AR-nNOS-NO activation. Background Aerobic exercise confers sustainable protection against cardiac hypertrophy and heart failure (HF). Nitric oxide synthase (NOS) and nitric oxide (NO) are known to play an important role in exercise-mediated cardioprotection, but the mechanism of NOS/NO stimulation during exercise… Read More

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Young & Old: Vitamin D, Resistance Training & Skeletal Muscle

Research Paper Title Does vitamin-D Intake during Resistance Training Improve the Skeletal Muscle Hypertrophic and Strength Response in Young and Elderly Men? – A Randomised Controlled Trial. Introduction Recent studies have shown that vitamin-D intake can improve skeletal muscle function and strength in frail vitamin-D insufficient individuals. The researchers investigated whether vitamin-D intake can improve… Read More

Research: Muscles; Big, Bigger & Not So Big!

Research Paper Title Differential Response of Skeletal Muscles to mTORC1 signaling during Atrophy and Hypertrophy. Background Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass. Inactivation of… Read More