Smoking Cessation, Glycaemic Control & Weight Gain: Any Link?

Current smoking is associated with a higher risk if type 2 diabetes, and the most beneficial thing anyone with this condition can do is to give up smoking. However, it is not quite that simple. A retrospective cohort study of 10,692 adult smokers with type 2 diabetes that used the Health Improvement Network, a large… Read More

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Cardiovascular Risk Factors, Type 2 Diabetes & Egg Consumption

Research Paper Title The Effect of a High-egg Diet on Cardiovascular Risk Factors in People with Type 2 Diabetes: The Diabetes and Egg (DIABEGG) study – A 3-mo Randomized Controlled Trial. Background Previously published research that examined the effects of high egg consumption in people with type 2 diabetes (T2D) produced conflicting results leading to… Read More

Do PCSK9 Inhibitors Reduce Cardiovascular Events?

Two investigational drugs from a new class of lipid lowering agents – the proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors – significantly reduce cardiovascular events, new exploratory analyses have shown. PCSK9 promotes the degradation of low density lipoprotein (LDL) receptors, so blocking its action increases the levels of receptor, which facilitates the clearance of LDL… Read More

What’s the Link between Genetically Low Vitamin D Concentrations & Increased Mortality?

Research Paper Title Genetically Low Vitamin D Concentrations and Increased Mortality: Mendelian Randomisation Analysis in Three Large Cohorts. Study Question Are genetically low 25-hydroxyvitamin D concentrations associated with increased mortality when a mendelian randomisation approach is used? Summary Answer Genetically low 25-hydroxyvitamin D concentrations were associated with increased all cause mortality, cancer mortality, and other mortality but… Read More

Turkish Military Personnel: Coronary Risk Factors & HDL

Research Paper Title Traditional Coronary Risk Factors in Healthy Turkish Military Personnel between 20 and 50 years old: Focus on High-density Lipoprotein Cholesterol. Background Previous studies presented the Turkish population as a typical example of nations with low levels of high-density lipoprotein cholesterol (HDL-c). Nevertheless, some recent studies opposed this suggestion. The researchers aimed to… Read More

Linking Metabolic Syndrome, CV Risk & Economic Development

Research Paper Title Dramatic Escalation in Metabolic Syndrome and Cardiovascular Risk in a Chinese Population Experiencing Rapid Economic Development. Background Metabolic syndrome (MetSyn) increases the incidence of cardiovascular disease. Information on changes in prevalence of MetSyn in developing countries is limited. This study aims to compare MetSyn prevalence and its associated vascular risk over the… Read More

Cardiovascular Risk of HDL: Niacin, Fibrates & CETP Inhibitors

Research Paper Title Effect of Cardiovascular Risk of the High Density Lipoprotein Targeted Drug Therapies Niacin, Fibrates, and CETP Inhibitors: Meta-analysis of Randomised Controlled Trials including 117 411 Patients. Study Question Do treatments to increase the level of high density lipoprotein (HDL) deliver the cardiovascular event reduction that might be expected from the strong relation… Read More