Discussing the Pathophysiology of Volumetric Muscle Loss (VML) Injury.

Research Paper Title Pathophysiology of Volumetric Muscle Loss Injury. Background Volumetric muscle loss (VML) injuries are prevalent in civilian and military trauma patients and are known to impart chronic functional deficits. The frank loss of muscle tissue that defines VML injuries is beyond the robust reparative and regenerative capacities of mammalian skeletal muscle. Given the… Read More

18YO: Exercise Capacity & Muscle Strength and Risk of Vascular Disease & Arrhythmia

Research Paper Title Exercise Capacity and Muscle Strength and Risk of Vascular Disease and Arrhythmia in 1.1 Million Young Swedish Men: Cohort Study. Study Question Is exercise capacity and muscle strength at age 18 years related to an increased risk of vascular disease and arrhythmia? Summary Answer High exercise capacity and muscle strength in late… Read More

Research: Muscles; Big, Bigger & Not So Big!

Research Paper Title Differential Response of Skeletal Muscles to mTORC1 signaling during Atrophy and Hypertrophy. Background Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass. Inactivation of… Read More