Obesity & Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is now more common than alcoholic liver disease owing to the rapid rise in the prevalence of obesity (Marchesini et al., 2008), and NAFLD is the most common cause of abnormal liver function tests (Clark et al., 2011). Its prevalence worldwide is thought to be approximately 20% in the general population… Read More

Mortality & Fruit and Vegetable Consumption

Research Paper Title Fruit and Vegetable Consumption and Mortality from All Causes, Cardiovascular Disease, and Cancer: Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies. Study Question What is the association between consumption of fruit and vegetables and risk of all cause, cardiovascular, and cancer morality? Summary Answer Evidence from prospective cohort studies shows that… Read More

Cardiovascular Risk of HDL: Niacin, Fibrates & CETP Inhibitors

Research Paper Title Effect of Cardiovascular Risk of the High Density Lipoprotein Targeted Drug Therapies Niacin, Fibrates, and CETP Inhibitors: Meta-analysis of Randomised Controlled Trials including 117 411 Patients. Study Question Do treatments to increase the level of high density lipoprotein (HDL) deliver the cardiovascular event reduction that might be expected from the strong relation… Read More