Research Paper Title:

Efficacy of Vitamin and Antioxidant Supplements in Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis of Randomised Controlled Trials.

Study Question:

Are vitamin and antioxidant supplements beneficial for the prevention of cardiovascular diseases?

Summary Answer:

The meta-analysis of randomised controlled trials found no evidence to support the use of vitamin and antioxidant supplements in the prevention of cardiovascular diseases.

What is Already Known and What This Paper Adds:

Previous randomised controlled trials have reported inconsistent findings regarding the efficacy of vitamin and antioxidant supplements in prevention of cardiovascular diseases, and there has been no published comprehensive meta-analysis.  The researchers found no evidence to support the use of vitmain or antioxidant supplements in the primary or secondary prevention of major cardiovascualr events.

Source: BMJ 2013;346:f10.

Related Article

• Effect of Antioxidant Vitamin Supplementation on Cardiovascular Outcomes: A Meta-Analysis of Randomized Controlled Trials (plosone.org)