Diabetes: Trials & Outcomes Linked?

Peripheral Vascular Disease
Peripheral Vascular Disease (Photo credit: Wikipedia)

Statistically it has been suggested that 1 in 10 people will soon carry the label of ‘diabetes’, and the world badly needs new ways of reducing the long term risks of this condition, such as coronary heart disease, peripheral vascular disease, blindness, and renal failure.

It has been suggested that the human race should have learnt by now that unless an intervention for diabetes can be shown to reduce such events, then it has no place in the medical profession’s arsenal of treatment – and this will inevitably require large, long trials in typical populations.

A piece in Diabetologia states that the majority of current trials in diabetes registered on ClinicalTrials.gov:

  • Exclude older people;
  • Are of short duration;
  • Involve drug therapy rather than preventive or non-drug interventions; and
  • Do not focus on important cardiovascular outcomes.

Source: BMJ 2013;346:f2325.

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