Determinants of Non- response in the EPIC-PANACEA Study

Research Paper Title

 

Determinants of Non- response to a Second Assessment of Lifestyle Factors and Body Weight in the EPIC-PANACEA Study.

 

Background

 

This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment of lifestyle factors and body weight in the European multi-centre EPIC-PANACEA study.

 

Methods

 

Over 500.000 participants from several centres in ten European countries were recruited between 1992 and 2000 were contacted 2–11 years later to update data on lifestyle and body weight. Length of follow-up as well as the method of approaching differed between the collaborating study centres. Non-responders were compared with responders using multivariate logistic regression analyses.

 

Results

 

Overall response for the second assessment was high (81.6%). Compared to postal surveys, centres where the participants completed the questionnaire by phone attained a higher response. Response was also high in centres with a short follow-up period. Non-response was higher in participants who were male (odds ratio 1.09 (confidence interval 1.07; 1.11), aged under 40 years (1.96 (1.90; 2.02), living alone (1.40 (1.37; 1.43), less educated (1.35 (1.12; 1.19), of poorer health (1.33 (1.27; 1.39), reporting an unhealthy lifestyle and who had either a low (<18.5 kg/m2, 1.16 (1.09; 1.23)) or a high BMI (>25, 1.08 (1.06; 1.10); especially ≥30 kg/m2, 1.26 (1.23; 1.29)).

 

Conclusions

 

Cohort studies may enhance cohort maintenance by paying particular attention to the subgroups that are most unlikely to respond and by an active recruitment strategy using telephone interviews.

 

Reference

 

May, A.M., Adema, L.E., Romaguera, D. et al. (2012) Determinants of Non- response to a Second Assessment of Lifestyle Factors and Body Weight in the EPIC-PANACEA Study. BMC Medical Research Methodology. 12(148).

 

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